Metal oxide-based biocompatible hybrid sorbent for the extraction and enrichment of catecholamine neurotransmitters and related compounds, and method of synthesis
AssigneeUniversity of South Florida
InventorsABDUL MALIK, ABDULLAH AWADH ALHENDAL
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Abstract
The subject invention concerns metal or metalloid oxide-based sol-gel hybrid sorbent and methods of synthesis. In one embodiment, the sorbent is a ZrO2 polypropylene oxide based sol-gel. The subject invention also concerns a hollow tube or capillary internally coated with a sorbent of the invention. Sorbent coated tubes and capillaries of the invention can be used in extraction and/or enrichment of samples to be analyzed for catecholamines and related compounds.
Claims19
A metal or metalloid oxide-based sol-gel hybrid sorbent composition prepared from a biocompatible polymer or ligand comprising one or more sol-gel active end groups.
A hollow tube or capillary coated on the inner surface with a metal or metalloid oxide-based sol-gel hybrid sorbent composition.
A method for preparing a metal or metalloid oxide-based sol-gel hybrid sorbent, wherein the method comprises synthesis by a hydrolytic sol-gel (HSG) method or synthesis by a non-hydrolytic sol-gel (NHSG) method;
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- a method for extraction and/or enrichment of one or more catecholamines, or catecholamine metabolites, or a related compound in a sample, the method comprising passing the sample through a hollow tube or capillary coated on the inner surface with a metal or metalloid oxide-based sol-gel hybrid sorbent composition, and then desorbing the product from the sorbent of the tube or capillary wall.
Dependencies are inferred from the claim text.