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US 2018/0001079 A1Published application
Vivo treatment of skin lesions by electrical nanopulses
AssigneePulse Biosciences, Inc.
InventorsJack Robert Weissberg, Gary Steven Lazar, Dong Yin
Life of this patent
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Abstract
This disclosure relates to an in vivo treatment of a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied. The pulse duration may be at least 0.01 nanoseconds at the full-width-at-half-maximum. This treatment may at least prevent growth of the lesion.
Claims23
A method of in vivo treatment of a skin lesion, the method comprising:
- selecting, based on a type of the skin lesion, a duration of an electrical pulse at a full-width-half-maximum and an amplitude of the electrical pulse, wherein the duration is at least 0.01 nanoseconds;
- determining at least one of a volume of the skin lesion or a surface area of the skin lesion;
- selecting, based on at least one of the volume of the skin lesion or the surface area of the skin lesion, a configuration of electrodes of a pulse delivery device;
- determining, prior to a start of a delivery of the electrical energy and based on the duration and the amplitude of the electrical pulse and on the configuration of the electrodes, a total number of electrical pulses to generate for a delivery of electrical energy per volume of the skin lesion of at least 10 mJ/mm3;
- setting, prior to the start of the delivery of the electrical energy, the duration, amplitude and the total number on a pulse generator connected to the pulse delivery device;
- and
- causing the delivery of the electrical energy of at least 10 mJ/mm3 to the skin lesion through the electrodes of the pulse delivery device.
4 more elements
16-18. (canceled)
22-25. (canceled)
28-34. (canceled)
Dependencies are inferred from the claim text.