Dry powder drug delivery system and methods
AssigneeMannKind Corporation
InventorsChad C. Smutney, Benoit Adamo, Brendan F. Laurenzi, P. Spencer Kinsey
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Abstract
A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation. The inhaler and cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, small organic molecules, peptides and proteins, including, hormones such as insulin and glucagon-like peptide 1 for the treatment of disease and disorders, for example, diseases and disorders, including endocrine disease such as diabetes and/or obesity.
Claims20
A medicament cartridge comprising:
- a powder container;
- a lid;
- and
- an internal volume,
- wherein the lid includes a deflector or stem protruding from an undersurface facing the internal volume to direct airflow entering the internal volume from a direction parallel to the lid to a substantially downward direction to a direction substantially parallel to the lid to a direction substantially perpendicular to the lid to exit the powder container.
Dependencies are inferred from the claim text.