Hyaluronic acid-based gels including lidocaine
AssigneeAllergan Industrie, SAS
InventorPierre F. Lebreton
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Abstract
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.
Claims6
A device for restoring fat loss-related tissue volume loss in the face, the device comprising:
- a syringe;
- a sterile viscoelastic gel contained in the syringe, the gel comprising hyaluronic acid crosslinked with 1,4-butanediol diglycidyl ether (BDDE), and including an amount of lidocaine.
The device of claim 2 wherein the syringe has an internal volume of about 0.4 mL to about 3 mL.
A device for restoring fat loss-related tissue volume loss in the face, the device comprising:
- a syringe having an internal volume between about 0.8 mL and about 2.5 mL;
- a sterile viscoelastic gel contained in the syringe, the gel comprising hyaluronic acid crosslinked with 1,4-butanediol diglycidyl ether (BDDE), and including 0.3% lidocaine.
Dependencies are inferred from the claim text.