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US 2018/0000950 A1Published application
Triglyceride otic formulations and uses thereof
AssigneeOtonomy, Inc.
InventorsRobert Savel, Zhanpeng Zhang, Scott Coleman, Fabrice Piu, Hong Qi
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Abstract
Disclosed herein are triglyceride based formulations, compositions, and methods for the treatment of otic diseases and conditions. Such triglyceride based formulations and compositions are derived from medium chain triglycerides and allow for the delivery of a variety of therapeutic agents to the outer, middle, and/or inner ear.
Claims30
An otic pharmaceutical formulation comprising:
- a) a therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof;
- and
- b) triglycerides comprising medium chain fatty acids;
- wherein the triglycerides are present in an amount that is sufficient to stabilize the therapeutic agent for injection into the ear, and wherein the otic pharmaceutical formulation comprises at least about 50% by weight of the triglycerides.
1 more element
Dependencies are inferred from the claim text.