Immunogenicity of an Optimized Synthetic Consensus DNA Vaccine for Porcine Epidemic Diarrhea Virus
AssigneeThe Trustees of the University of Pennsylvania
InventorsDavid Weiner, Emma L. Reuschel, Karuppiah Muthumani
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Abstract
Provided herein is a vaccine comprising a Porcine Epidemic Diarrhea Virus (PEDV) antigen. The antigen can be a consensus antigen. Also disclosed herein is a method of treating a porcine in need thereof, by administering the vaccine to the porcine.
Claims38
An immunogenic composition comprising a nucleic acid molecule, wherein the nucleic acid molecule comprises a nucleic acid sequence having at least about 90% identity over an entire length of the nucleic acid sequence selected from the group comprising SEQ ID NO:1 and SEQ ID NO:4.
An immunogenic composition comprising a nucleic acid molecule, wherein the nucleic acid molecule encodes a peptide comprising an amino acid sequence having at least about 90% identity over an entire length of the amino acid sequence selected from the group comprising SEQ ID NO:2 and SEQ ID NO:5.
An immunogenic composition comprising a peptide comprising an amino acid sequence having at least about 90% identity over the entire length of the amino acid selected from the group comprising SEQ ID NO:2 and SEQ ID NO:5.
A nucleic acid molecule comprising a nucleic acid sequence having at least about 90% identity over an entire length of the nucleic acid sequence selected from the group comprising SEQ ID NO:1 and SEQ ID NO:4.
A peptide comprising an amino acid sequence having at least about 90% identity over the entire length of the amino acid sequence selected from the group comprising SEQ ID NO:2 and SEQ ID NO:5.
Dependencies are inferred from the claim text.