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US 2018/0000920 A1Published application
Pharmaceutical compositions containing clostridium difficile toxoids a and b
AssigneeSanofi Pasteur Biologics, LLC
InventorsC. Russell MIDDAUGH, Richard FAHRNER, Peter CIARAMETARO
Life of this patent
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Abstract
This invention relates to compositions including Clostridium difficile toxins and/or toxoids and corresponding methods. The compositions of the invention include one or more excipients that increase stability and/or decrease aggregation of the toxins.
Claims22
1-43. (canceled)
A composition comprising:
- (a) a toxoid of Clostridium difficile toxin A and/or B;
- and
- (b) a sugar or sugar alcohol selected from sucrose, sorbitol, dextrose, and trehalose, at a concentration of 1-30%.
Dependencies are inferred from the claim text.