Vaccine compositions for use against enterotoxigenic escherichia coli
AssigneeWashington University
InventorJames M. FLECKENSTEIN
Life of this patent
Estimating the term…
Abstract
The present disclosure provides vaccine compositions for use against enterotoxigenic Escherichia coli (ETEC) comprising EtpA and EatA. EtpA and EatA are prevalent amount diverse ETEC isolates and display significant sequence conservation. In an aspect, the disclosure encompasses a vaccine composition comprising EtpA and EatA. In another aspect, the disclosure encompasses a method of protecting against intestinal colonization of enterotoxigenic Escherichia coli (ETEC) in a subject. The method comprises administering to the subject an effective amount of a vaccine composition comprising EatA and EtpA.
Claims23
A vaccine composition, the vaccine composition comprising EtpA and EatA.
(canceled)
A method of protecting against intestinal colonization of enterotoxigenic Escherichia coli (ETEC) in a subject, the method comprising administering to the subject an effective amount of a vaccine composition comprising EatA and EtpA.
A method of preventing or treating ETEC-associated diarrhea, the method comprising administering to the subject an effective amount of a vaccine composition comprising EatA and EtpA.
(canceled)
-26. (canceled)
Dependencies are inferred from the claim text.