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US 2018/0000903 A1Published application
Tablets Comprising GLP-1 Agonist and Enteric Coating
AssigneeNovo Nordisk A/S
InventorsBirgitte Nissen, Flemming S. Nielsen, Patrick W. Garibay
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Abstract
The present invention relates to solid pharmaceutical compositions for oral administration comprising a GLP-1 agonist, an absorption enhancer which is a salt of medium-chain fatty acid, and an enteric coating as well as uses thereof.
Claims21
A solid pharmaceutical composition comprising i) a core comprising a salt of a medium-chain fatty acid and a GLP-1 agonist;
- and ii) a first coating which dissolves at pH 6.0 or higher.
A solid pharmaceutical composition comprising i) a core comprising a salt of a medium-chain fatty acid and a GLP-1 agonist;
- and ii) a first coating consisting of an anionic copolymer coating, wherein said anionic copolymer coating comprises methacrylate copolymer, and wherein said methacrylate copolymer comprises a) 10-30% w/w methyl methacrylate, b) 50-70% w/w methyl acrylate, and c) 5-15% w/w methacrylic acid.
(canceled)
Dependencies are inferred from the claim text.