High molecular weight polysaccharide that binds and inhibits virus
AssigneeWorld Force Technologies, LLC
InventorsThomas W. Konowalchuk, Jack Konowalchuk
Life of this patent
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Abstract
This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods of inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further includes methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses.
Claims36
A composition that binds to a virus and inhibits said virus, said composition comprising:
- an isolated polysaccharide comprising an arabinofuranosyl residue, a galactopyranosyl residue, and a galactouronic acid;
- and
- a catechin polymer;
- wherein said composition is soluble in water;
- and
- wherein said composition binds to a virus and reduces the infectivity or pathogenecity of said virus.
A composition that binds to a virus and inhibits said virus, said composition comprising:
- an isolated polysaccharide comprising an arabinofuranosyl residue, a rhamnopyranosyl residue, a galactopyranosyl residue, a glucopyranosyl residue, a mannopyranosyl residue, and a galactouronic acid;
- and
- a non-carbohydrate aromatic polymer;
- wherein said composition comprises about 40 to about 44 percent oxygen, about 44 to about 48 percent carbon, about 3 to about 6 percent hydrogen;
- and about 0.1 to about 1 percent nitrogen;
- wherein said composition is soluble in water;
- and
- wherein said composition binds to a virus and reduces the infectivity or pathogenecity of said virus.
A method of preparing a composition that binds a virus, said method comprising:
- preparing a substantially homogeneous aqueous mixture or solution of plant material from one or more plants of the Vitaceae family;
- contacting said mixture with an ion exchange resin and recovering the colored product;
- and
- further purifying the colored product by removing components that can pass through a dialysis filter that generally passes molecules having a molecular weight of a 5×105 Daltons or less to produce a composition that binds a virus.
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Dependencies are inferred from the claim text.