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AssigneeThe Regents of the University of California
InventorsMitsuko L. Yamamoto, Robert H. Schiestl, Ramune Reliene, James Borneman, Laura L Presley, Jonathan Braun
Estimating the term…
Inoculation of ATM-deficient mice with probiotic microorganisms, such as L. johnsonii, changed immune parameters, decreased a marker of DNA damage and increased the lifespan of the mice. Compositions and methods described herein are useful for the treatment and prevention of Ataxia telangiectasia and other cancer-prone disease, such as p53 deficiency-associated cancers. Compositions and methods of the present invention are also useful for treating and preventing radiation-induced toxicity to normal tissue in a subject being exposed to radiation, Compositions and methods of the invention can increase lifespans in a simple, non-invasive manner.
1-97. (canceled)
A food or beverage product comprising Lactobacillus johnsonii 456.
The food or beverage product of claim 1, wherein the product is a nutritional whole food, drink, mineral water, soup, replacement food, nutritional bar, confectionery, fermented or unfermented milk-based product, yoghurt product, milk-based powder, enteral nutritional product, baby and/or infant composition, fermented or unfermented cereal-based product, ice cream, chocolate, coffee, mayonnaise, tomato puree, salad dressing, milk, yoghurt, cheese, fermented milks, milk-based fermented products, ice creams, cereal-based products, fermented cereal-based products, milk-based powders, baby and infant formulas, food product of confectionery type, chocolate, cereals or animal feed.
A probiotic composition comprising Lactobacillus johnsonii 456.
A method of altering a subject's microbiome, comprising administering to the subject a composition comprising Lactobacillus johnsonii 456.
Dependencies are inferred from the claim text.