PHARMACEUTICAL COMPOSITION AND THERAPEUTIC COMBINATION COMPRISING A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR AND HMG CoA REDUCTASE INHIBITORS
AssigneeDezima Pharma B.V.
InventorsJohn FORD, Patrick ROUND, John KASTELEIN
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Abstract
The present invention relates to a pharmaceutical composition and a therapeutic combination comprising a novel cholesteryl ester transfer protein (CETP) inhibitor and a HMG CoA Reductase inhibitor, which may be used in the treatment of subjects suffering from or having an increased risk for cardiovascular diseases, in particular hyperlipidemia or mixed dyslipidemia.
Claims25
A pharmaceutical composition comprising:
- (a) a compound of the formula:
- or a pharmaceutically
- acceptable salt thereof;
- (b) at least one HMG CoA reductase inhibitor or a pharmaceutically acceptable salt thereof;
- and
- (c) one or more pharmaceutically acceptable excipients.
10-24. (canceled)
27-28. (canceled)
A method of treating a subject suffering from or having an increased risk for cardiovascular diseases comprising administering to said subject in need thereof a pharmaceutically effective amount of said therapeutic combination according to claim 10.
Dependencies are inferred from the claim text.