US 2018/0000776 A1 · FORMULATION FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS

Abstract

The present invention relates to a formulation of Spinacea oleracea useful for the prevention or treatment of osteo-health related disorders. The present invention relates to the field of pharmaceutical formulation that provides extract, fractions, pure compound isolated from natural sources and formulation thereof useful for the prevention and treatment of various medical indications. Further, this invention relates to conditions associated with estrogen dependent or independent diseases (primary/secondary osteoporosis) or syndromes or disorders preferably relating to cartilage such as osteoarthritis caused in humans and animals. Furthermore, this invention relates to achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly, the present invention relates to the processes for the preparation of biologically active extracts, from Spinacea oleracea from the family Amaranthaceae their pharmaceutically acceptable excepients and compositions of the principal aspect of the present invention.

Claims20

Dependent claims

A formulation comprising;

a. an extract and/or a fraction comprising compounds 5,3′,4′-trihydroxy-3-methoxy-6,7-methylenedioxy-flavone in the range of 0.01 to 0.07% and 5,7,3′,4′-tetrahydroxy-3,6-dimethoxy-flavone in the range of 0.004-0.05%;
b. pharmaceutically acceptable carriers and additives;
c. surfactant;
and
d. co-surfactant,
wherein extract and/or fraction is obtained from Spinach and the formulation is used in prevention and/or treatment of bone related disorders.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

15/635,457Filed 28 Jun 2017

Priority

IN 2016110226401 Jul 2016

Published

4 Jan 2018

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

A61K 31/357
Having oxygen as the only ring hetero atom, e.g. fungichromin: having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A61K 9/0019
Galenical forms characterised by the site of application: injectable compositions; Intramuscular, intravenous, arterial, subcutaneous…
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 9/0095
Galenical forms not covered by A61K9/02 - A61K9/7023: drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets…

Formulation for the prevention and treatment of bone related disorders

Life of this patent

Formulation for the prevention and treatment of bone related disorders

Life of this patent

Abstract

Claims20