Methods for the regeneration of articular cartilage in vivo
AssigneeUniversity of Iowa Research Foundation
InventorsJames A. Martin, Yin Yu, Dong Rim Seol, Aliasger K Salem, Behnoush Khorsand Sourkohi, Anh-Vu T Do, Marc Brouillette
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Abstract
A pharmaceutical composition is provided that is useful to enhance the repair of articular cartilage, to treat a joint injury or to prevent, inhibit or treat osteoarthritis in a mammal. The composition may include an effective amount of an isolated protein that is a chemoattractant for chondrogenic progenitor cells and/or an effective amount of an isolated protein that is a chondro genic factor or a nucleic acid sequence that encodes a chondrogenic factor.
Claims20
A pharmaceutical composition comprising at least one naturally occurring polymer comprising an effective amount of an isolated protein that is a chemoattractant for chondrogenic progenitor cells and an effective amount of an isolated protein that is a chondrogenic factor, or nucleic acid sequence that encodes a chondrogenic factor.
Dependencies are inferred from the claim text.