Wax Foamable Vehicle and Pharmaceutical Compositions Thereof
AssigneeFoamix Pharmaceuticals Ltd.
InventorsDov Tamarkin, Rita Keynan, David Schuz, Tal Berman
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Abstract
Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.
Claims21
1-46. (canceled)
A foamble composition comprising a carrier and a liquefied hydrocarbon gas propellant, wherein the carrier comprises:
- a) a liquid wax comprising at least one fatty acid and/or at least one fatty alcohol;
- b) a stabilizer component comprising a non-ionic surface active agent and/or a polymeric agent;
- and
- c) water;
- wherein the ratio of the carrier to the gas propellant is about 100:3 by weight to about 100:35 by weight;
- and
- wherein, upon release from a pressurized container, the foamable composition produces a breakable foam.
Dependencies are inferred from the claim text.