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AssigneeSederma
InventorsOlivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
Estimating the term…
The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid. The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.
Peptidic compound comprising from 2 to 10 amino acids for use in cosmetics and dermatology domains comprising at least one amino acid selected from a lysine, a lysine analog or a hydroxylated derivative of these amino acids, on which a carboxylic acid is grafted by a peptidic bound on the nitrogen of the lateral chain, said carboxlic acid comprising at least a cycle or a heterocycle.
(canceled)
Method for increasing the activity on the synthesis of macromolecules of the ECM of skin of a peptidic compound comprising at least a lysine (K, Lys), an analog of lysine, or a derivative of these aminoacids, wherein a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain of the at least one lysine (K, Lys), lysine analog or derivative of said aminoacids, said carboxylic acid comprising at least a carbon cycle or heterocycle having 5, 6 or 7 atoms, being aromatic or not, which said (poly)cycle or (poly)heterocycle optionally comprises a —OH, —O—, —CO—, —S—, —N═, —NH—, —N═C—NH— function, as well as a charged nitrogen function.
Dependencies are inferred from the claim text.