Preservation and transport of an ex vivo biological sample comprising ultrasound application
AssigneeInstitut D'Investigacions BiomèDiques August Pi I Sunyer (Idibaps)
InventorCarmen Peralta
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Abstract
The present invention relates to a device for transport and preservation of an ex vivo biological sample and corresponding method. The device (1) comprises a chamber (2) for containing the biological sample (100), delimitated by walls (4) made of a thermal insulating material. The device, furthermore, incorporates cooling means (6) that keep the temperature inside the chamber (2) below the temperature outside the device (1). Finally, an ultrasound system suitable for generating and applying ultrasound on the biological sample (100) is provided. The invention also proposes a method for transport and preservation which combines applying cooling and ultrasound to reduce cell damage in the biological sample.
Claims26
A device (1) for transport and preservation of an ex vivo biological sample (100) for subsequent transplant in a living human being or animal, comprising a chamber (2) for containing said biological sample (100), delimitated by walls (4) made of a thermal insulating material and cooling means (6) for keeping the temperature inside said chamber (2) below the temperature outside said device (1), characterized in that it further comprises an auxiliary container (14) for containing a preservation solution, without external oxygen delivery and for containing said biological sample (100) immersed in said preservation solution and at least an ultrasound system suitable for generating and applying ultrasound on said biological sample (100).
(canceled)
A method for transport of an ex vivo biological sample (100) for subsequent transplant in a living human being or animal, characterized in that it comprises the following steps:
- [a] removing blood from said biological sample (100) under cold conditions and rapidly cooling said biological sample (100),
- [b] keeping said biological sample (100) immersed in a preservation solution without external oxygen delivery by placing said biological sample in a chamber (2) delimitated by walls (4) made of a thermal insulating material, and
- [c] irradiating said sample with ultrasound.
Dependencies are inferred from the claim text.