Micro-devices for disease detection

A method for detecting a mechanical or electric property of a biological subject, comprising:

• providing a piezo-electric micro-device comprising a piezo-electric material forming a probe with a supporting point in the micro-device, an electronically conductive material, a material that is neither piezo-electric nor electronically conductive, wherein the piezo-electric material is placed between the electronically conductive material and the material that is neither piezo-electric nor electronically conductive;
• and
• contacting the piezo-electric micro-device with the biological subject to be detected, wherein the piezo-electric micro-device detects the mechanical, acoustical, or electric property of the biological subject upon contacting it and converts the mechanical, acoustical, or electric property to generate an electric or mechanical response, and transferring the electric, acoustical, or mechanical response thus generated through the electrically conductive material to a recording device or data analyzer.