Biomarker Kit for Metastatic Breast Cancer Prognosis and Uses Thereof
AssigneeUniversity of Maryland, Baltimore
InventorAikaterini Kontrogianni-Konstantopoulos
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AssigneeUniversity of Maryland, Baltimore
InventorAikaterini Kontrogianni-Konstantopoulos
Estimating the term…
Provided herein are kits for detecting and quantifying the level of a metastatic cancer biomarker(s) in a patient. The kits may contain a detection and quantifying means, such as, biomarker specific antibodies. Also provided are methods for determining a prognosis, a stratification and/or monitoring of a metastatic cancer in a patient. The level or activity of at least two biomarkers, such as obscurin, PI3K, E-cadherin, or N-cadherin is measured in a patient sample and compared to corresponding biomarkers in a control sample. A significant difference in the level or activity of the biomarkers between the patient sample and control is indicative of a metastatic cancer. In addition a method for treating a metastatic breast cancer via administration of a PI3K inhibitor and an agent that increases expression of obscurin is provided.
A kit, comprising:
A method for determining a prognosis, a stratification and/or for monitoring of a metastatic breast cancer in a patient, comprising the steps of:
A method for determining a prognosis, a stratification and/or for monitoring of a metastatic cancer in a patient, comprising the steps of:
A method for treating metastatic breast cancer, comprising the step of:
Dependencies are inferred from the claim text.