Methods for detecting and quantifying analytes using gas species diffusion

A method of detecting the presence of a plurality of selected analytes in a test sample comprising:

• (a) exposing at least a first and second gas sensors to a first gas sample comprising a known gas species, wherein the first gas sensor is derivatized with a first selected analyte binder and the second gas sensor is derivatized with a second selected analyte binder, and determining a control sensor response profile for the first gas sensor and a control sensor response profile for the second gas sensor;
• (b) exposing the at least first and second gas sensors to a test sample;
• (c) exposing the at least first and second gas sensors to a second gas sample comprising the known gas species and determining a test sample sensor response profile for the first gas sensor and a test sample sensor response for the second gas sensor;
• and
• (d) determining the presence or absence of a first analyte and a second analyte in the test sample by comparing the first test sample sensor response profile with the first control sensor response profile and the second test sample sensor response profile with the second control sensor response profile.