Cd6 antibody for treatment of t-cell mediated diseases or disorders
AssigneeThe Cleveland Clinic Foundation
InventorFeng Lin
Life of this patent
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Abstract
A method of treating a T-cell mediated disease in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6 is described. Humanized antibodies useful for the method are also described.
Claims22
A method of treating a T-cell mediated disease or disorder in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6.
A humanized antibody or antigen-binding fragment thereof having binding specificity for CD6, wherein the antibody selected from the group of antibodies consisting of Fab2, Fab4, and Fab6, or variants thereof including only conservative sequence modifications.
A kit comprising a humanized antibody or fragment thereof that specifically binds to CD6, and a package for holding the antibody.
Dependencies are inferred from the claim text.