Use of binding molecule specifically binding to precursor of brain-derived neurotrophic factor
AssigneeShanghai Yile Biotechnology Limited
InventorsChangqi Li, Huamao Wang, Ruping Dai, Xiumei Cai, Xinfu Zhou
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Abstract
Disclosed herein is use of a binding molecule which specifically binds to a precursor of brain-derived neurotrophic factor (proBDNF). The binding molecule for proBDNF, especially a monoclonal antibody against proBDNF, can be used to prevent, mitigate or treat autoimmune diseases.
Claims29
A method for preventing, mitigating or treating an autoimmune disease comprising administering to a subject in need thereof a binding molecule which specifically binds to a precursor of brain-derived neurotrophic factor.
A method for inhibiting an interleukin (IL) production, comprising administering to a subject in need thereof a binding molecule which specifically binds to a precursor of brain-derived neurotrophic factor.
A method for inhibiting an interferon (IFN) or a tumor necrosis factor production, comprising administering to a subject in need thereof a binding molecule which specifically binds to a precursor of brain-derived neurotrophic factor.
Dependencies are inferred from the claim text.