Tuberculosis Compositions And Methods Of Treating Or Preventing Tuberculosis
AssigneeAeras
InventorsRavi P. Anantha, Thomas G. Evans, Aurelio M. Bonavia
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Abstract
The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
Claims22
A composition or fusion protein comprising at least three Mycobacterium tuberculosis (Mtb) antigens, wherein the Mtb antigens are chosen from Rv1009, Rv3136, Rv3615c, Rv2628, Rv2034, and Rv3136 N-terminus.
A composition or fusion protein comprising at least two Mycobacterium tuberculosis (Mtb) antigens, wherein the Mtb antigens are Rv1733 and Rv2626c.
A composition or fusion protein comprising at least three Mycobacterium tuberculosis (Mtb) antigens, wherein the Mtb antigens are chosen from Ag85A, Ag85B, Rv3407, RpfA, RpfC, and RpfD.
Dependencies are inferred from the claim text.