Pro-survival compounds

A compound according to formula (I):

• wherein:
• R1 is H, aryl, substituted aryl, alkyl, CH(CH3)R5, or CH2R5;
• R5 is aryl, substituted aryl, heteroaryl, substituted heteroaryl or heterocyclic;
• X is NZ, O, CH2 or S, or alternatively X may not be present;
• Z is H or alkyl;
• R2 and R3 are each independently selected from H, alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, or alternatively R2 and R3 together form an aromatic or heteroaromatic ring, optionally comprising one or more substituents;
• A is CH2, CH2CH2 or CH(CH3);
• Y is C(═O)NZ′, C(═O)O, SO2NH, NHC(═O), C(═O)NHC(═O), NH, or 0;
• Z′ is H, alkyl, alkoxyalkyl, or wherein Z′ and R4 together form a 5- or 6-membered ring heterocyclic group with at least one N atom;
• n is 0, 1, 2 or 3;
• W is H or alkyl, wherein when n is greater than 1, each W is independently selected from H or alkyl;
• R4 is H, alkyl, cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, OR6, heterocyclic, alkylamino, C≡N or C(═O)R7;
• R6 is H, alkyl, haloalkyl, aryl, alkoxyalkyl;
• and
• R7 is hydroxy, alkoxy, amino or alkylamino.