Carbazole derivatives

A compound of Formula (I)

• or a salt thereof, wherein:
• the two dotted lines represent either two single or two double bonds;
• and R1b and R2b are present only if said two dotted lines are two single bonds;
• Q is:
• R1a is:
• (i) H, —CN, —CF3, —CH3, —CR8aR8bOH, —CR8aR8bCR8aR8bOH, —CH(OH)CH2OH, —NHR9, —C(O)NR10aR10b, —C(O)(morpholinyl), —C(O)(piperazinyl), or —C(O)(methyl piperazinyl);
• or
• R1b, when present, is H or —CH3, provided that if R1a is H then R1b is also H;
• R2a is H, F, or Cl, provided that if R1a is other than H then R2a is H;
• R2b, when present, is the same as R2a;
• R3 is H, F, or Cl;
• R4 is H, F, Cl, or —CH3;
• R5a is H, F, Cl, —OCH3, or —OCF3;
• R5b is H, F, Cl, —OCH3, or —OCF3;
• R6a is H, —CH3 or cyclopropyl;
• R6c is H, —CH3 or cyclopropyl;
• R7a is —C(O)CH═CH(R11), —C(O)C≡CR12, or —S(O)2CH═CH2;
• R7b is —C(O)CH═CH2;
• R7c is —C(O)CH═CH2 or —C(O)C≡CR12;
• R7d is —CN, —C(O)CH═CH2, or —C(O)C≡CR13;
• R7e is —CH═CH2 or —C≡C13;
• R7f is pyrrolidinyl substituted with R7c, —CH═CHC(O)(morpholinyl), or —CH═CHC(O)(pyrrolidinyl);
• R8a is H or —CH3;
• R8b is H or —CH3;
• R9 is C1-4 alkyl;
• R10a and R10b are independently H or —CH3;
• R11 is H or —CH3;
• R12 is H, C1-4 alkyl, or cyclopropyl;
• and
• R13 is H, C1-4 alkyl, or cyclopropyl;
• with the provisos that:
• (a) if Q is
• and R7d is —CN or —C(O)CH═CH2, then R3 is H;
• and
• (b) if the dotted lines represent two single bonds, then:
• (i) Q is not
• (ii) R11, if present, is H;
• and
• (iii) the compound of Formula (I) is not: