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US 2017/0362175 A1Published application
Novel forms of apremilast
AssigneeJohnson Matthey Public Limited Company
InventorPadmini KAVURU
Life of this patent
Estimating the term…
Abstract
The present disclosure is directed to novel forms of apremilast and pharmaceutical compositions comprising any of the novel forms of apremilast. Also provided are processes for the preparation of novel forms of apremilast.
Claims16
A form of apremilast selected from the group consisting of Form H, Form I, Form J, Form K and Form M;
- wherein:
- Form H has an X-ray powder diffraction pattern comprising peaks, in terms of 2-theta, at about 7.47 and about 26.38;
- Form I has an X-ray powder diffraction pattern comprising peaks, in terms of 2-theta, at about 26.51 and about 17.93;
- Form J has an X-ray powder diffraction pattern comprising peaks, in terms of 2-theta, at about 10.81 and about 27.26;
- Form K has an X-ray powder diffraction pattern comprising peaks, in terms of 2-theta, at about 11.40 and about 13.66;
- and
- Form M has an X-ray powder diffraction pattern comprising peaks, in terms of 2-theta, at about 7.35 and about 11.34.
4 more elements
A form of apremilast selected from the group consisting of Form H, Form I, Form J, Form K and Form M;
- wherein:
- Form H has an X-ray powder diffraction pattern substantially as shown in FIG. 3;
- Form I has an X-ray powder diffraction pattern substantially as shown in FIG. 4;
- Form J has an X-ray powder diffraction pattern substantially as shown in FIG. 5;
- Form K has an X-ray powder diffraction pattern substantially as shown in FIG. 6;
- and
- Form M has an X-ray powder diffraction pattern substantially as shown in FIG. 7.
4 more elements
A form of apremilast selected from the group consisting of Form H, Form I, Form J, Form K and Form M;
- wherein:
- Form H has an X-ray powder diffraction pattern comprising peaks at d-spacing, in terms of Angstroms, of about 11.820 and about 3.376;
- Form I has an X-ray powder diffraction pattern comprising peaks at d-spacing, in terms of Angstroms, of about 3.360 and about 4.944;
- Form J has an X-ray powder diffraction pattern comprising peaks at d-spacing, in terms of Angstroms, of about 8.180 and about 3.268;
- Form K has an X-ray powder diffraction pattern comprising peaks at d-spacing, in terms of Angstroms, of 7.756 and about 6.477;
- and
- Form M has an X-ray powder diffraction pattern comprising peaks at d-spacing, in terms of Angstroms, of about 12.022 and about 7.796.
4 more elements
Dependencies are inferred from the claim text.