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US 2017/0362170 A1Published application
Hepatitis c antiviral compositions and methods
OwnerGary Dinneen EWART, Carolyn Anne LUSCOMBE +1inventors
InventorsGary Dinneen EWART, Carolyn Anne LUSCOMBE, Michelle MILLER
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Abstract
The present invention relates to novel compositions having anti-viral activity and in particular it relates to synergistic compositions active against Hepatitis C virus (HCV). The invention also relates to methods for retarding, reducing or otherwise inhibiting HCV growth and/or functional activity.
Claims16
A composition comprising a compound of Formula I:
- Wherein
- R1 is
- and
- n is 1;
- Q is
- wherein R2 is straight or branched chain alkyl;
- and X is hydrogen, and pharmaceutically acceptable salts
- thereof,
- in combination with at least one additional agent having anti-viral activity selected from the group consisting of an interferon (IFN), and a nucleoside analogue, wherein the IFN is IFN a-2b and wherein the nucleoside analogue is selected from the group consisting of 2′-C-methyladenosine and 2′-C-methylcytidine.
6 more elements
Dependencies are inferred from the claim text.