Self-assembling peptides comprising non-ionic polar amino acids
Assignee3-D Matrix, Ltd.
InventorsEun Seok Gil, Marc Rioult, Keiji Nagano, Karl Patrick Gilbert, Toshiro Kiyofuji, Yuya Hasegawa
Life of this patent
Estimating the term…
Abstract
Compositions, peptide solutions and macroscopic scaffolds of self-assembling peptides consisting essentially of non-ionic, polar amino acids are provided. Particular peptides include those comprising or consisting essentially of serine, threonine, tyrosine, cysteine, glutamine, asparagine, methionine, tryptophan, hydroxy-proline, and combinations thereof. Methods of sterilizing the self-assembling peptides, and scaffolds comprising the peptides are also provided.
Claims78
A composition comprising a self-assembling peptide consisting essentially of non-ionic, polar amino acids.
A peptide solution comprising a self-assembling peptide consisting essentially of non-ionic, polar amino acids.
A method for sterilizing peptides comprising:
- providing a peptide solution comprising a self-assembling peptide consisting essentially of non-ionic, polar amino acids;
- treating the peptide solution at a predetermined temperature and a predetermined pressure for a predetermined period of time to sterilize the peptide solution, the predetermined temperature and predetermined pressure selected to provide conditions of saturated steam.
A macroscopic scaffold comprising self-assembling peptides consisting essentially of non-ionic, polar amino acids.
Dependencies are inferred from the claim text.