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US 2017/0360987 A1Published application
Hydrophilization and antifouling of enhanced metal surfaces
AssigneeCardiac Pacemakers, Inc.
InventorsDanielle Frankson, Joseph T. Delaney, JR., Mary M. Byron, Adam McGraw, David R. Wulfman, Kylee M. Lersch
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Abstract
A coating for a roughened metal surface of an implantable medical device includes a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface.
Claims20
A coating for a roughened metal surface of an implantable medical device, the coating comprising:
- a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface by an inorganic ether bond.
An implantable medical device comprising:
- a roughened metal surface;
- and
- a coating disposed on at least a portion of the roughened metal surface, the coating comprising a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface by an inorganic ether bond.
A method for coating a roughened metal surface of an implantable medical device, the method comprising:
- activating at least a portion of the roughened metal surface by forming hydroxyl groups on the surface;
- and
- treating the activated roughened metal surface with a poly(ethylene glycol) to covalently bond the poly(ethylene glycol) directly to the roughened metal surface by an inorganic ether bond.
Dependencies are inferred from the claim text.