Radioembolic particles
AssigneeABK Biomedical Incorporated
InventorsDaniel BOYD, Robert Joseph ABRAHAM, Xiaofang ZHANG, Sharon KEHOE, James CLARKE
Life of this patent
Estimating the term…
Abstract
Provided are radiopaque compositions comprising one or more of yttrium (Y), strontium (Sr), gallium (Ga), and silicon, or oxides and salts thereof. The composition can comprise a combination of Y2O3, SrCO3, Ga2O3, and SiO2, and optionally MnO2, and TiO2. Other compositions comprise SrCO3, Ga2O3, TiO2, MnO2, and SiO2. The composition can be a particulate material. The compositions are useful for radioembolization to treat tumors.
Claims12
A composition comprising:
- about 0.10 to about 0.17 mole fraction of Y2O3;
- about 0.02 to about 0.15 mole fraction of SrCO3;
- about 0.05 to about 0.30 mole fraction of Ga2O3;
- and
- about 0.5 to about 0.8 mole fraction of SiO2.
A composition comprising:
- about 0.05 to about 0.15 mole fraction of SrCO3;
- about 0.10 to about 0.30 mole fraction of Ga2O3;
- about 0.000 to about 0.005 mole fraction of MnO2;
- about 0.00 to about 0.10 mole fraction of TiO2;
- and
- about 0.5 to about 0.75 mole fraction of SiO2.
The composition of any of the preceding claims, wherein the composition is radiopaque.
The composition of any of the preceding claims, wherein the composition comprises particles having a particle size from about 15 to about 80 microns.
An irradiated composition produced by the irradiation of a composition of any of the preceding claims.
Dependencies are inferred from the claim text.