Novel tilapia virus and uses thereof

(canceled)

-8. (canceled)

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(canceled)

An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:

• 12 or comprising an amino acid sequence that has at least about 80% sequence identity to SEQ ID NO:
• 12.

-22. (canceled)

An isolated antibody that specifically binds to a polypeptide encoded by the nucleic acid having a sequence selected from the group consisting of SEQ ID NOs:

• 1-11, fragments and variants thereof or a polypeptide comprising the amino acid sequence of SEQ ID NO:
• 12, fragments and variants thereof.

(canceled)

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(canceled)

-32. (canceled)

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-39. (canceled)

-45. (canceled)

An immunogenic composition comprising a killed virus and/or attenuated virus comprising a Tilapia Lake Virus polypeptide.

(canceled)

(canceled)

An immunogenic composition comprising a fusion polypeptide, wherein the fusion polypeptide comprises a Tilapia Lake Virus polypeptide, a fragment or variant thereof and at least one polypeptide, or fragment, from an additional virus.

-60. (canceled)

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-77. (canceled)

A kit for screening for Tilapia Lake Virus, which comprises (a) at least one primer which is a synthetic nucleic acid comprising at least about 10 nucleotides of the isolated nucleic acid having a nucleic acid sequence of any of SEQ ID NOs:

• 1-11 or a nucleic acid sequence complementary to the a nucleic acid having the nucleic acid sequence of any of SEQ ID NOs:
• 1-11 to amplify nucleic acids obtained from a biological sample, and, optionally, (b) primers or adapters suitable to enable sequencing of the amplified nucleic acid and determination of the presence of the Tilapia Lake Virus.

(canceled)