US 2017/0360897 A1Published application

Polypeptide and polypeptide complex for suppressing tumor metastasis and treating leukemia as well as preparation method therefor and application thereof

AssigneesNational Center for Nanoscience and Technology, China, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

InventorsChen Wang, Hongyang Duan, Yanlian Yang, Haiyan Xu, Xiaojin Li, Hua Guo, Hanyi Xie, Yue Yu

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Abstract

The present invention provides a group of polypeptides and a complex formed by the polypeptides and human serum albumin, a method for improving the solubility of the group of polypeptides in a salt solution by combining the polypeptides with human serum albumin, a method for preparing the complex formed by the group of polypeptides and human serum albumin, and an application of the group of polypeptides and the complex formed by the polypeptides and human serum albumin in the preparation of drugs for suppressing tumor metastasis and treating leukemia.

Claims12

Dependent claims

(canceled)

Dependencies are inferred from the claim text.

Facts

Application: 15/328,355Filed 1 Jul 2015
Priority: CN 201410353810.523 Jul 2014
Published: 21 Dec 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 38/385
Albumins: serum albumin
A61K 38/08
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: peptides having 5 to 11 amino acids
A61K 38/16
Medicinal preparations containing peptides: peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 47/42
Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates: proteins; Polypeptides; Degradation products thereof; Derivatives…