Vasopressin formulations for use in treatment of hypotension

A method of increasing blood pressure in a human in need thereof, the method comprising:

• a) providing a unit dosage form for intravenous administration, wherein the unit dosage form comprises:
• i) from about 0.1 units/mL to about 1 unit/mL of vasopressin or a pharmaceutically-acceptable salt thereof;
• ii) acetic acid, acetate, or a combination thereof;
• iii) 0-2% vasopressin degradation products;
• iv) dextrose;
• and
• v) water;
• and
• b) administering the unit dosage form to the human by intravenous administration;
• wherein:
• the unit dosage form has a pH of no greater than 4.1;
• the administration provides to the human from about 0.01 units of vasopressin or the pharmaceutically-acceptable salt thereof per minute to about 0.1 units of vasopressin or the pharmaceutically-acceptable salt thereof per minute;
• and the human is hypotensive.