Use of polyacetylenic glycosides for suppression of granulocytic myeloid-derived suppressor cell activities and tumor metastasis
AssigneeAcademia Sinica
InventorsNing-Sun YANG, Wen-Chi WEI, Sheng-Yen LIN, Pei-Wen HSIAO, Yet-Ren CHEN
Life of this patent
Estimating the term…
Abstract
A pharmacological composition for use in inhibiting differentiation, functional activities, and population of granulo-cytic myeloid-derived suppressor cells (gMDSCs) and/or suppressing, tumor metastasis in a subject in need thereof is disclosed. The composition comprises a therapeutically effective amount of Bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the B. pilosa extract, and a pharmaceutically acceptable carrier.
Claims16
A method for suppressing, reducing, blocking and/or preventing tumor metastasis in a subject in need thereof, comprising administering to the subject in need thereof a pharmacological composition comprising:
- (i) a therapeutically effective amount of Bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the B. pilosa extract;
- and
- (ii) a pharmaceutically acceptable carrier.
A method for inhibiting differentiation, functional activities, and population of granulocytic myeloid-derived supressor cells (gMDSCs) and/or suppressing metastatic cancer in a subject in need thereof, comprising administering to the subject in need thereof a pharmacological composition comprising:
- (i) a therapeutically effective amount of Bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the B. pilosa extract;
- and
- (ii) a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.