Methods for producing dopaminergic neurons and uses thereof
AssigneeUniversite Laval
InventorsMartin Lévesque, Audrey Chabrat
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Abstract
The present application relates to a stem cell, a precursor or progenitor cell in which Plexin C1 has been inactivated, a dopaminergic (DA) neuron in which Plexin C1 has been inactivated, methods of preparing same and uses thereof for the treatment of Parkinson's disease.
Claims20
A method for treating a subject with Parkinson's disease, the method comprising implanting dopaminergic (DA) neurons in which Plexin C1 have been inactivated into the striatum and/or in the midbrain of the subject.
A method for treating a subject with Parkinson's disease, the method comprising administering dopaminergic (DA) neurons in which Plexin C1 have been inactivated and allowing the DA to be implanted into the striatum and/or in the midbrain of the subject.
Dependencies are inferred from the claim text.