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AssigneeNational University Corporation Kumamoto University
InventorsKunimasa OHTA, Naofumi ITO
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An object of the present invention is to provide a pluripotent cell having high safety in application to regenerative medicine, and a method for production thereof. Another object of the present invention is to provide a pluripotent cell, particularly, having less concern for safety, such as a problem of cancerization of a cell, and the presence of bacteria in a cell, and a method for production thereof. According to the present invention, there is provided a method for producing a pluripotent cell from a somatic cell. The method comprises a step of inducing reprogramming of a somatic cell, by contacting the cell with a ribosome fraction derived from an organism. Further, according to the present invention, there is provided a composition for inducing reprogramming of a cell, comprising a ribosome fraction derived from an organism.
-40. (canceled)
A method for inducing reprogramming of an isolated somatic cell or cancer cell of a mammal, comprising a step of culturing the cell with a reprogramming agent, wherein the agent is a ribosome fraction derived from a prokaryote or a eukaryote and is selected from a group consisting of a 70S ribosome fraction, a 80S ribosome fraction, a 30S ribosome fraction, and a 50S ribosome fraction.
A composition for inducing cell reprogramming, comprising a ribosome fraction derived from a prokaryote or a eukaryote, wherein the ribosome fraction is selected from a group consisting of a 70S ribosome fraction, a 80S ribosome fraction, a 30S ribosome fraction, and a 50S ribosome fraction.
Dependencies are inferred from the claim text.