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US 2017/0360828 A1Published application
Treatment of Rheumatoid Arthritis Using Noble Gas Mixtures
AssigneeNobilis Therapeutics, Inc.
InventorsVlad Bogin, Thomas Ichim
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AssigneeNobilis Therapeutics, Inc.
InventorsVlad Bogin, Thomas Ichim
Estimating the term…
The invention disclosed provides means of inhibiting, ameliorating, and/or treatment of rheumatoid arthritis through the use of Noble gas containing mixtures. In one embodiment, the invention provides means of reducing inflammation and immune associated pathology through administration of Noble gas mixtures. In one specific embodiment, Xenon gas is administered to a patient in need at concentrations and frequencies sufficient to inhibit inflammatory and autoimmune processes. In another embodiment Noble gas mixtures are administered to reduce pain and provide symptomatic relieve to a patient suffering from rheumatoid arthritis. In another embodiment the use of Noble gas containing mixtures is disclosed as a means of reducing joint destruction through inhibition of matrix metalloprotease production and activity.
A method of inhibiting an autoimmune process comprising the steps of:
The method of claim 24, wherein said inflammatory marker is selected from a group comprising of:
A method increasing sensitivity to an anti-cytokine biologic in a rheumatoid arthritis patient, said method comprising administration of a Noble gas containing mixture.
A method of inducing antigen specific tolerance, said method comprising generation of a particle containing a Noble gas together with an antigen to which tolerance is desired.
A method of reducing pain in a patient with rheumatoid arthritis comprising administration of a therapeutically sufficient concentration and frequency of a Noble gas.
Dependencies are inferred from the claim text.