Cortexolone 17alpha-benzoate for use in the treatment of tumours
AssigneeCosmo Technologies Ltd.
InventorMara GERLONI
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Abstract
The present invention provides certain cortexolone derivatives of formula (I), and the same for use as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. Another aspect of the invention relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of said pharmaceutical compositions as antitumor medicinal products.
Claims24
1-14. (canceled)
A pharmaceutical composition comprising a compound having the formula:
- and at least one physiologically acceptable excipient.
(canceled)
(canceled)
20-28. (canceled)
A method of treating precancerous lesions, dysplasias, metaplasias and tumor diseases in a subject in need thereof, comprising administrating to said subject a therapeutically effective amount of a compound having formula:
- or a pharmaceutical composition comprising said compound.
A method of treating tumors, in a subject in need thereof, the method comprising administrating to said subject a therapeutically effective amount of a compound having formula:
- or a pharmaceutical composition comprising said compound to said subject.
A method of treating a disease or disorder mediated by glucocorticoid, in a subject in need thereof, the method comprising administrating to said subject a therapeutically effective amount of a compound having formula:
- or a pharmaceutical composition comprising said compound.
Dependencies are inferred from the claim text.