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US 2017/0360791 A1Published application
Pharmaceutical compositions for increasing the bioavailability of poorly soluble drugs
AssigneeAstex Pharmaceuticals, Inc.
InventorsRajashree Joshi-Hangal, Sanjeev Redkar, Chunlin Tang
Life of this patent
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Abstract
Pharmaceutical compositions comprising poorly soluble compounds, such as BCS class II or class IV drugs (e.g. amuvatinib), are provided. The pharmaceutical compositions are effective for increasing the bioavailability of the compounds. Related kits and methods are also provided.
Claims18
A pharmaceutical composition comprising:
- a) amuvatinib, or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof;
- b) a surfactant polymer, or a pharmaceutically acceptable salt thereof;
- c) a tocopherol, or a pharmaceutically acceptable salt thereof;
- and
- d) a fatty acid, a fatty acid ester, or a pharmaceutically acceptable salt thereof.
2 more elements
-18. (canceled)
Dependencies are inferred from the claim text.