Methods for Treating a Cytomegalovirus Infection
AssigneeThe J. David Gladstone Institutes
InventorLeor S. Weinberger
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Abstract
The present disclosure provides a method for inhibiting cytomegalovirus (CMV) replication in a cell infected with CMV, the method comprising contacting the cell with a bisbenzimidazole compound. The present disclosure provides a method of treating a CMV infection in an individual, the method comprising administering to the individual an effective amount of a bisbenzimidazole compound.
Claims27
A method for inhibiting cytomegalovirus (CMV) replication in a cell infected with CMV, the method comprising contacting the cell with a bisbenzimidazole compound.
A method of treating a cytomegalovirus (CMV) infection in an individual, the method comprising administering to the individual an effective amount of a bisbenzimidazole compound.
A method of inhibiting cytomegalovirus replication in an organ or tissue, the method comprising contacting the organ or tissue in vitro or ex vivo with a bisbenzimidazole compound.
A method of reducing the likelihood that a transplant recipient will become infected with cytomegalovirus from a donor organ or tissue, the method comprising:
- a) contacting the organ or tissue in vitro or ex vivo with a bisbenzimidazole compound, thereby producing a bisbenzimidazole compound-treated organ or tissue;
- and
- b) transplanting the bisbenzimidazole compound-treated organ or tissue into the transplant recipient.
Dependencies are inferred from the claim text.