Use of zileuton for the treatment of nasal polyps in cystic fibrosis patients
AssigneeCornerstone Therapeutics, Inc.
InventorsJoseph K. Han, Carmen Dell'Anna
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Abstract
The present invention provides methods of treating nasal polyps in cystic fibrosis patients using zileuton. The present invention also provides methods of treating nasal polyps in cystic fibrosis patients using zileuton in combination with surgical debridement and/or steroid treatment.
Claims25
A method of treating nasal polyps in a patient having cystic fibrosis comprising administering to the patient an effective amount of zileuton.
A method of treating nasal polyps in a patient having cystic fibrosis comprising administering to the patient an effective amount of zileuton and an effective amount of a steroid.
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A method of treating nasal polyps in a patient having cystic fibrosis comprising
- i) debriding the nasal polyps;
- and
- ii) administering to the patient an effective amount of zileuton.
-15. (canceled)
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A method of reducing the likelihood of developing nasal polyps in a patient having cystic fibrosis and a Pseudomonas infection comprising administering to the patient an effective amount of zileuton.
A method of reducing the likelihood of developing nasal polyps in a patient having cystic fibrosis comprising testing the patient for a Pseudomonas infection and, wherein the patient has a Pseudomonas infection, administering a therapeutically effective amount of zileuton to the patient for a period of time sufficient to reduce the likelihood of development of nasal polyps.
Dependencies are inferred from the claim text.