Back to results
US 2017/0360741 A1Published application
Pharmaceutical Formulation for Histone Deacetylase Inhibitors
AssigneeTetraLogic Shape UK Ltd
InventorsTodd W. Chappell, Keith A. Johnson
Life of this patent
Estimating the term…
Abstract
A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.
Claims24
A method of treating a proliferative disorder in a subject in need thereof, said method comprising cutaneously administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising
- an active pharmaceutical ingredient (API) compound represented by the following structural formula
- at least one acidifying agent;
- and
- a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent,
- wherein the pharmaceutical composition has a measured pH of from about 3 to about 5;
- the API is present in an amount of 0.1 to 5.0% (w/w);
- and
- the at least one non-aqueous solvent comprises ethanol.
5 more elements
Dependencies are inferred from the claim text.