Methods and Drug Therapies for Patency of Occluded Blood Vessels Following Angioplasty
AssigneeNephroGenesis LLC
InventorJames A. Tumlin
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Abstract
The present disclosure relates to a method of maintaining luminal patency of a blood vessel following vessel injury, the method including administering a composition comprising at least one lysyl oxidase inhibitor and D-penicillamine to a subject in need thereof Compositions to support the methods are also provided.
Claims18
A method of maintaining luminal patency of a blood vessel following vessel injury, the method comprising administering a composition comprising at least one lysyl oxidase inhibitor and D-penicillamine to a subject in need thereof.
A method of reducing serial angioplasty or procedures to restore luminal patency in a blood vessel or reducing smooth muscle cell migration into an area of a blood vessel wall following blood vessel injury, the method comprising administering a composition comprising at least one lysyl oxidase inhibitor and D-penicillamine to a subject in need thereof.
(canceled)
A method of inhibiting cross-linking between collagen and/or elastin fibers, the method comprising administering a composition comprising at least one lysyl oxidase inhibitor and D-penicillamine to a subject in need thereof.
A composition comprising at least one lysyl oxidase inhibitor and D-penicillamine in a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.