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US 2017/0360703 A1Published application
Amphiphilic polymer
AssigneesLG Chem, Ltd., LG Household & Health Care Ltd.
InventorsJeong Ae Yoon, Su Jeong Kim, Sun Hwa Lee, Woo Sun Shim, Sung Soo Yoon, Chang Hwan Ju, Jung A Kim, Nae Gyu Kang
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Abstract
The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.
Claims23
An amphiphilic polymer, comprising:
- a first block (A);
- and
- a second block (B) which is phase-separated from the first block (A) and includes a polymerization unit (B1) of an acrylic monomer or vinyl-based monomer of which a homopolymer has a solubility parameter of less than 10.0 (cal/cm3)1/2 and a polymerization unit (B2) of a polymerizable monomer having a functional group which is capable of forming a hydrogen bond,
- wherein a weight ratio (B1:B2) of the polymerization unit (B1) of an acrylic monomer or vinyl-based monomer of which a homopolymer has a solubility parameter of less than 10.0 (cal/cm3)1/2 to the polymerization unit (B2) of a polymerizable monomer having a functional group which is capable of forming a hydrogen bond in the second block (B) is in a range of 1:9 to 9:1.
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Dependencies are inferred from the claim text.