Apparatus for compound dispersion
AssigneeBiogen MA Inc.
InventorAjay Verma
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Abstract
Methods and apparatuses for dispersing a compound within the patient are described. In one embodiment, an effective amount of a compound may be present in the cerebrospinal fluid of a patient and a force may be applied to the torso of the patient sufficient to enhance the convection of the cerebrospinal fluid. In another embodiment, a bolus including a compound may be injected into the cerebrospinal fluid of a patient. The volume of the bolus may be between about 5% and 30% of the total volume of the cerebrospinal fluid of the patient.
Claims44
A method for dispersing a compound within an intrathecal neuraxis of a patient, the method comprising:
- applying a force to a torso of a patient to enhance convection of cerebrospinal fluid that includes an effective amount of a compound to enhance dispersion of the compound.
The method of claim 9, wherein the total force change of the force is between or equal to about 0 and 1 PSI.
A method for dispersing a compound within a patient, the method comprising:
- applying a force to a torso of the patient sufficient to enhance convection of lymph that includes an effective amount of a compound contained in the lymph node to enhance dispersion of the compound.
A method for dispersing a compound within a patient, the method comprising:
- injecting a bolus including a compound into cerebrospinal fluid of a patient, wherein a volume of the bolus is between or equal to about 5% and 30% of a total volume of the cerebrospinal fluid of the patient.
A device for dispersing a compound within a patient, the device comprising:
- an element constructed to apply a force to a torso of a patient, wherein a peak magnitude, force gradient, frequency, wave form, and/or and wave/pause sequence of the force is selected to enhance convection of the cerebrospinal fluid of the patient.
Dependencies are inferred from the claim text.