Nanoelectroablation control and vaccination
AssigneePulse Biosciences, Inc.
InventorsRichard Lee Nuccitelli, Jon Casey Berridge, Zachary Mallon, Mark Kreis, Brian Athos, Pamela Nuccitelli
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AssigneePulse Biosciences, Inc.
InventorsRichard Lee Nuccitelli, Jon Casey Berridge, Zachary Mallon, Mark Kreis, Brian Athos, Pamela Nuccitelli
Estimating the term…
Techniques for treating a tumor and vaccinating against cancer are described. The techniques include treating the tumor by positioning electrodes over an interface between the tumor and non-tumor tissue and applying sub-microsecond pulsed electric fields. The positioning is facilitated by an imaginary contour line of a threshold value of the electric field. In an example, the imaginary contour line is overlaid over images that include the tumor such that the electrodes are properly positioned over the tumor. The techniques also include vaccinating against cancer by passing sub-microsecond pulsed electric fields through tumor cells of a subject sufficient to cause the tumor cells to express calreticulin on surface membranes. The tumor cells are extracted and introduced with the expressed calreticulin into the subject or another subject, thereby providing a vaccination.
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An apparatus for visualizing an electric field surrounding a surgical instrument, the apparatus comprising:
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A non-transitory computer readable storage medium storing instructions that, upon execution on a computing system, cause the computing system to:
A computing system comprising:
Dependencies are inferred from the claim text.