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US 2017/0360354 A1Published application
Microelectrode with Hemoglobin or Iron Sensor and Methods of Guiding Same
AssigneeGreenville Neuromodulation Center
InventorsErwin Montgomery, He Huang
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Abstract
Provided herein are microelectrodes and methods of localizing and targeting the same. The microelectrodes include electrochemical or biological sensors, an array of electrical contacts along a long axis of the microelectrode, or both. The methods of localizing and targeting use statistical manipulations to reduce the errors inherent in spike train analyses.
Claims25
A microelectrode comprising:
- a body comprising a proximal end, a distal end, and a sidewall there between defining a longitudinal axis, the body comprising an electrically non-conductive material and at least one portion comprising an electrically conductive material;
- and
- at least one electrochemical or biological biosensor disposed within or on the body.
A method of detecting the presence of a hematoma in a patient's brain during neurophysiological monitoring, comprising:
- advancing a microelectrode along a path within the brain of a patient, the microelectrode comprising:
- a body comprising a proximal end, a distal end, and a sidewall therebetween defining a longitudinal axis, the body comprising an electrically non-conductive material and at least one portion comprising an electrically conductive material;
- and
- at least one electrochemical or biological biosensor disposed within or on the body;
- and
- detecting the presence or absence of a chemical or biological analyte, wherein the presence of the chemical or biological analyte is indicative of the presence of a hematoma.
3 more elements
Dependencies are inferred from the claim text.