Culture vessel, measurement device, culture method, and culture device
AssigneeHitachi, Ltd.
InventorsGuangbin ZHOU, Masaharu KIYAMA, Yumiko IGARASHI
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Abstract
The present invention provides a culture vessel and a measuring device for measuring a cell sheet thickness nondestructively during culturing. A culture vessel having a lid 4 has a float 8 installed in the interior and the float is structured so as to be uplifted by a culture medium in the culture vessel. Further, a cell sheet thickness measuring device having a sensor head 10 having a light-emitting element 10A and a light-receiving element 10B to detect a positional variation of the float in the vertical direction and a controller 11 to process a signal of the sensor head is configured.
Claims15
A culture vessel comprising a lid, a sidewall, a culture plane, and a float installed in the interior and capable of being uplifted by a culture medium over the culture plane.
A measuring device comprising:
- a culture vessel including a lid, a sidewall, a culture plane, and a float installed in the interior and capable of being uplifted by a culture medium over the culture plane;
- a sensor head installed outside the culture vessel and measuring a positional variation of the float in the vertical direction in the interior of the culture vessel;
- and
- a controller to process a measurement signal of the sensor head.
A culture method of a cell culture sheet for culturing a cell culture sheet while the positional variation in the vertical direction is measured on the basis of a measurement signal of a sensor head installed outside a culture vessel having a float capable of being uplifted by a culture medium over a culture plane in the interior and measuring a positional variation of the float in the vertical direction in the interior of the culture vessel.
A culture apparatus comprising:
- a culture vessel having a float capable of being uplifted by a culture medium over a culture plane in the interior;
- a sensor head installed outside the culture vessel and measuring a positional variation of the float in the vertical direction in the interior of the culture vessel;
- a controller to process a measurement signal of the sensor head;
- a culture medium exchange unit to discharge/inject the culture medium to the culture vessel;
- a mixed gas exchange unit to discharge/inject a mixed gas to the culture vessel;
- and
- a control section to control the controller, the culture medium exchange unit, and the mixed gas exchange unit.
Dependencies are inferred from the claim text.