Method of manufacturing intramedullary nails made of chitosan for long bones fractures treatment

Method of manufacturing intramedullary nails made of chitosan for long bones fractures treatment, consisting of the following stages:

• preparation of powdered chitosan, obtained in deacetylation process of the chitin from marine organisms,
• dissolving chitosan in water and adding acetic acid, while stirring, until an uniform solution is obtained,
• coating the inner surface of the mold with said uniform solution and filling the thus formed gel die with said chitosan solution,
• forming the blank intramedullary nail in the die,
• subjecting the blank to coagulation bath in NaOH solution and neutralizing bath in deionized water,
• drying the blank, characterized in that the powdered chitosan is dissolved in water to obtain a 5% solution, into which a 70-90% acetic acid is added and after the formation of the blank intramedullary nail and carrying a coagulating bath and neutralization bath it is subjected to a crosslinking bath in a solution formed from 0.5 to 9% of sodium tri-polyphosphate and 0.5% to 3% Na3PO4 for 24 to 48 hours in temperature of 50° C. to 140° C. and then it is subjected to the drying process, for a period of 6 to 10 days, and finally the surface of the blank is treated to form the intramedullary nail.