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AssigneeThe Texas A&M University System
InventorsVenu Varanasi, Pranesh Aswath, Philip Kramer, Megen Velten, Azhar Ilyas
Estimating the term…
Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of Si—O—N—P. These coatings and/or layers may be continuous, on the surface or discontinuous (e.g., patterned, grooved), and may be provided on silica surfaces, metal (e.g., titanium), ceramic, and combination/hybrid materials. Methods of producing an implantable device, such as a load-bearing or non-load-bearing device, such as a bone or other structural implant device (load-bearing), are also presented. Craniofacial, osteogenic and disordered bone regeneration (osteoporosis) uses and applications of devices that include at least one surface that is treated to include a nanoscale or microscale layer or coating of Si—O—N—P are also provided. Methods of using the treated and/or coated devices to enhance enhanced vascularization and healing at a treated surface of a device in vivo, is also presented.
A device comprising at least one treated surface having a composition comprising a phosphorous-doped silicon oxynitride, wherein the treated surface comprises an amorphous, stoichiometric, non-stoichiometric, or crystalline silicon oxynitrophosphide (SizOxNyPw) layer.
A method for preparing a treated surface to include a Si—O—N—P layer, said method comprising:
A method for enhancing vascularization at a surface comprising:
Dependencies are inferred from the claim text.